Renal imidazoline preferring sites and solute excretion in the rat
نویسندگان
چکیده
منابع مشابه
Renal excretion of renin in the rat.
The renal excretion of renin infused intravenously was studied in anesthetized rats. The renin in the urine was adsorbed onto DEAE cellulose and selectively eluted for separate assay on the rat blood pressure preparation. The influence of saline loading, furosemide, mercuric chloride, and maleic acid was determined by following the changes in renin excretion. Both mercuric chloride and maleic a...
متن کاملCharacterization of I2 imidazoline and sigma binding sites in the rat and human stomach.
Radioligand binding experiments were carried out to identify and characterize nonadrenoceptor [3H]idazoxan binding sites and [3H](1, 2-di-(2-tolyl)guanidine) binding sites in the rat and human stomach. Furthermore, we examined two selected aspects of their potential functional significance. Binding of [3H]idazoxan (Kd = 11.1 nM and 12.4 nM, respectively) and [3H]DTG (Kd = 932 nM and 242 nM, res...
متن کاملCharacterization of I2 Imidazoline and s Binding Sites in the Rat and Human Stomach
Radioligand binding experiments were carried out to identify and characterize nonadrenoceptor [H]idazoxan binding sites and [H](1,2-di-(2-tolyl)guanidine) binding sites in the rat and human stomach. Furthermore, we examined two selected aspects of their potential functional significance. Binding of [H]idazoxan (Kd 5 11.1 nM and 12.4 nM, respectively) and [H]DTG (Kd 5 932 nM and 242 nM, respecti...
متن کاملEffects of acute increases in the excretion of solute and water on renal acid excretion in man.
It is well established that renal acid excretion can be influenced by certain tubular mechanisms that operate independently of systemic acid-base equilibrium. Thus, the stimulus for sodium reabsorption (1, 2), the competition between potassium and hydrogen ions for secretion (3), and the penetrating ability of anions present in the glomerular filtrate (4-6) are factors known to affect acid excr...
متن کاملDevelopment of renal potassium excretion capacity in the neonatal rat.
We investigated the capacity of newborn rats to excrete an acute potassium load to understand the development of a renal potassium excretion system. Three groups of the rats (7-14 d) were used to collect urine periodically over 6 h after oral infusion of potassium: control (no potassium loading) and low- and high-potassium-loaded rats. In the low-potassium-loaded group, infused with about 0.6 m...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1993
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1993.tb13480.x